The sulphatase of ox liver. II. The purification and properties of sulphatase A.

The sulphatase of ox liver. 3. Further observations on sulphatase B and an investigation of the origin of fractions A and B.

The sulphatase of ox liver. 7. The intracellular distribution of sulphatases A and B.

Involvement of sperm sulphatases in early sperm-zona interactions in the hamster.

Sulphatase preparations from Abalone entrails, the limpet Patella vulgata and ox liver, as well as artificial substrates for these enzymes, were used in the hamster in vitro fertilization system to study the possible roles of sperm sulphatases in sperm-zona pellucida interactions. p-nitrophenyl sulphate, p-nitrocatechol sulphate, ascorbate 2-sulphate, as well as D-glucopyranose and D-galactopyr...

Synthesis and Biological Screening of 1,3-Dialkyl Derivatives of 4-(2’5-Dioxopyrrolidine-3-yl) Phenyl Sulphinic Acid as Inhibitors of Oestrone Sulphatase

     1,3-dialkyl 3-phenylpyrrolidine-2, 5-diones were modified to produce potential steroid sulphatase inhibitors. These modifications were aimed at producing compounds, which could be expected to bind reasonably well to the active site of the steroid sulphatase enzyme but could not be hydrolyzed readily by the enzyme due to the covalent S-C bond present. In this regard the sulphinic acid deriv...

Quantitation of acid phosphatase and aryl sulphatase in rat hepatic parenchymal and kupffer cells.

The two acid hydrolases ‘acid phosphatase’ (orthophosphoric monoester phosphohydrolase, EC 3.1.3.2) and ‘aryl sulphatase’ (aryl-sulphate sulphohydrolase, EC 3.1.6.1) are both enzymes which are known to be present in the lysosomes of almost all cell types [cf. l] . Histochemical studies have revealed apparent activity of acid phosphatase in both hepatic parenchymal and Kupffer cells [2,3] , and ...